1.Verify Mailbox Existence
Use Exchange Admin Center (EAC) or PowerShell:
Get-Mailbox -Identity user@example.com
Confirm the mailbox is active and not in a disconnected or soft-deleted state.
2.Recreate Mail Profile
- Go to Control Panel โ Mail โ Show Profiles.
- Delete the corrupted profile and create a new one with correct credentials.
3.Flush DNS and Autodiscover Cache
- Run in Command Prompt (Admin):
- ipconfig /flushdns
- Delete Outlook Autodiscover cache from:
- %LOCALAPPDATA%\Microsoft\Outlook\RoamCache
4.Check AD and Exchange Replication
- Ensure that all domain controllers and Exchange servers are fully synced.
- Use: repadmin /replsummary and Get-ExchangeServer | Test-ServiceHealth
5.Review Mailbox Permissions
- Ensure the user or service account has appropriate Full Access or Send As rights.
Optional Step (If Applicable)
- If the mailbox was recently migrated, ensure Outlook is connecting to the correct Exchange version or Office 365 endpoint.
Run Outlook in Safe Mode:
- Outlook.exe /safe